3 Results for "

Oryza sativa L.

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Oryza sativa L." in MCE Product Catalog:

2,6-Dimethoxy-1,4-benzoquinone
2,6-Dimethoxy-1,4-benzoquinone
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Cat. No.: HY-N1677
CAS No.: 530-55-2
Category:  

Infection Quinones other families Metabolic Disease Benzene Quinones Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .
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Isopimaric acid
Isopimaric acid
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Cat. No.: HY-N3463
CAS No.: 5835-26-7
Category:  

Other Terpenoids Pinus nigra Arn. Pinaceae Terpenoids Plants

Target:  

Akt mTOR Apoptosis Autophagy Reactive Oxygen Species (ROS) Potassium Channel Sodium Channel Calcium Channel PINK1/Parkin Oxidative Phosphorylation Wnt Bacterial

Isopimaric acid is a coniferous tree defense compound. Isopimaric acid binds to AKT and inhibits mTOR phosphorylation, thereby regulating the AKT/mTOR pathway. Isopimaric acid inhibits oxidative stress, inflammation, microglial migration, apoptosis, autophagic flux, ornithine decarboxylase activity, breast cancer proliferation and metastasis, and fungal spore germination. Isopimaric acid also induces M2 microglial polarization, mitochondrial damage, ROS accumulation, starvation-induced colon cancer cell apoptosis, and breast cancer cell cycle arrest. Isopimaric acid activates potassium channels, regulates sodium channels and calcium channels, reduces myocardial excitability, and improves arrhythmia. Isopimaric acid acts as an oxidative substrate for CYP6BW1/3, down-regulates PINK1/Parkin, and regulates calcium homeostasis, oxidative phosphorylation, EMT, and the Wnt pathway. Isopimaric acid exhibits activity against drug-resistant Staphylococcus aureus, repels feeding, and promotes the growth of rice seedlings. Isopimaric acid is suitable for research related to epilepsy, tumors, drug-resistant bacterial infections, atrial fibrillation, hypertension, hyperlipidemia, pulmonary tuberculosis, etc .
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Spicifernin
Spicifernin
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Cat. No.: HY-N20618
CAS No.: 129514-40-5
Category:  

Natural Products Microorganisms

Target:  

Endogenous Metabolite

Spicifernin is a plant growth regulator produced by the fermentation of Cochliobolus sativus. Spicifernin promotes the elongation of roots, stems and the second leaf sheath of rice seedlings at low concentrations; while it inhibits the elongation of roots and stems of rice seedlings at high concentrations .
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